Abi-1 Polyclonal Antibody, 50ul Cellular Function Assays Mediator is recruited to promoters

Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors

an adenosine receptor of A2A subtype

Belongs to the G-alpha family

Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription factor activity

which may be necessary for the downstream signaling in response to cell-cell adhesion

Abi-1 Polyclonal Antibody, 50ul Cellular Function Assays Mediator is recruited to promotersABI1 encodes a member of the Abelson interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein (abl interactor 1) plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates