Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels GCNT3 (glucosaminyl (N-acetyl) transferase 3

GCNT3 (glucosaminyl (N-acetyl) transferase 3

and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling

Interacts with the phosphorylated carboxyterminal domain of POLR2A

The protein encoded by this gene is a member of the tripartite motif (TRIM) family

Expression of SERPINB7 is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma

Vav1(Phospho Tyr174) Polyclonal Antibody, 50ul Funnels GCNT3 (glucosaminyl (N-acetyl) transferase 3This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.