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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries Alpha chains of type IV

SKU: 28169162804

4.0
PLN141.00 PLN174.00

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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries Alpha chains of type IVCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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Description

Alpha chains of type IV collagen have a non-collagenous domain (NC1) at their C-terminus| frequent interruptions of the G-X-Y repeats in the long central triple-helical domain (which may cause flexibility in the triple helix)| and a short N-terminal triple-helical 7S domain

This gene encodes a male meiotic metaphase chromosome-associated acidic protein

including a non-AUG (CUG) codon

The long non-coding RNA transcripts interact with a variety of proteins

Several transcript variants encoding different isoforms of supervillin have been described

CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries Alpha chains of type IVCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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