Keratin 8 Polyclonal Antibody, 100ul Serological Pipets The activation of this protein

The activation of this protein is dependent upon the binding of cytokines to their receptors

These domains are found in proteins which participate in protein and DNA interactions which occur during chromatin restructuring or transcription

This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL)

The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair

some of them leading to cellular transformation (PubMed: 25642963

Keratin 8 Polyclonal Antibody, 100ul Serological Pipets The activation of this proteinThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal