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ITA11 Polyclonal Antibody, 50ul Molecular Sciences Several upstream open reading frames

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ITA11 Polyclonal Antibody, 50ul Molecular Sciences Several upstream open reading framesThis gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this

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Description

Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins

while defects in this gene are associated with multiple types of cancer

Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor

Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis

and it is believed to play a major role in human palatogenesis

ITA11 Polyclonal Antibody, 50ul Molecular Sciences Several upstream open reading framesThis gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this

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