c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology PPARs form heterodimers with retinoid

PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes

The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions

the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS

Several alternatively spliced transcript variants encoding different isoforms have been found for this gene

Two alternately spliced transcripts encoding two protein isoforms have been identified

c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology PPARs form heterodimers with retinoidThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF