NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation It is an ATPase and

It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process

a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators

although its function has not been well established

and stress-induced genes

The protein encoded by this gene interacts with several other proteins

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation It is an ATPase andProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.