HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases The family members are characterized

The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity

The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes

The protein encoded by MCM3AP (minichromosome maintenance complex component 3 associated protein) is a MCM3 binding protein

The protein encoded by XRCC5 (X-ray repair cross complementing 5) is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5

HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases The family members are characterizedHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it