RAB21 Polyclonal Antibody, 20ul Cell Labeling & Imaging The telomeric and centromeric copies

The telomeric and centromeric copies of this gene are nearly identical and encode the same protein

High levels also detected in liver

X-linked syndrome (IPEX)

The crystal structure of the complex formed by this protein and XRCC4 has been resolved

and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function

RAB21 Polyclonal Antibody, 20ul Cell Labeling & Imaging The telomeric and centromeric copiesThis gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by