GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Disruption of VEGFA in mice

Disruption of VEGFA in mice resulted in abnormal embryonic blood vessel formation

This gene is found in the small histone gene cluster on chromosome 6p22-p21

Phosphorylated upon DNA damage

Appears to play no role in the unfolded-protein response

Two splice variants have been found for this gene

GRK 2(Phospho Ser29) Polyclonal Antibody, 20ul 3D Cell Culture Consumables Disruption of VEGFA in miceThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.