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p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis 12-alpha-dihydroxy-4-cholesten-3-one

SKU: 29848799986

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p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis 12-alpha-dihydroxy-4-cholesten-3-oneThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

12-alpha-dihydroxy-4-cholesten-3-one

Mutations in this gene are associated with forebrain defects

RIN1 is localized primarily to the plasma membrane

from peptides and arylamides

Most members of family 1 have two conserved glutamic acid residues| which are required for enzymatic activity

p53(Phospho Thr18) Polyclonal Antibody, 100ul Cell Function Analysis 12-alpha-dihydroxy-4-cholesten-3-oneThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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