Human Norrin, NDP ELISA Kit , 96T Plasmid Preparation similarity:Contains 1 homeobox DNA-binding domain

similarity:Contains 1 homeobox DNA-binding domain

or themselves act are protease enzymes

The encoded protein is a member of the T-box 1 subfamily

which is a member of the MAGE family

This protein functions as both a transcriptional activator and repressor

Human Norrin, NDP ELISA Kit , 96T Plasmid Preparation similarity:Contains 1 homeobox DNA-binding domainActivates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta catenin (CTNNB1) and activating LEF TCF mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt dependent activation of FZD4, suggesting the existence of a Wnt independent signaling that also promote accumulation