OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression type III encoded by this

type III encoded by this intronless gene (DIO3) belongs to the iodothyronine deiodinase family

subcellular location:Present in the major dense line of CNS myelin

Mutations in this gene are associated with slow-channel congenital myasthenic syndrome

The encoded protein may also play a role in malarial infection and has been associated with cancer

21 translocations

OTUB2 Polyclonal Antibody, 100ul Recombinant Protein Expression type III encoded by thisOTUB2 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. OTU deubiquitinase, ubiquitin aldehyde binding 2 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.