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CD22 Polyclonal Antibody, 100ul[BT-AP07329] Protein Analysis An important paralog of this

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CD22 Polyclonal Antibody, 100ul[BT-AP07329] Protein Analysis An important paralog of thisalternative products: Additional isoforms seem to exist,Contains 4 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2 containing phosphatases.,Mediates B cell B cell interactions. May be involved in the localization of B cells in lymphoid tissues. Binds sialylated

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Description

An important paralog of this gene is TAAR9

Mutations in this gene can cause chromosome instability and VACTERL syndrome with hydrocephalus

encode distinct proteins (PMID:9207021)

This protein may also play a role in genome stability and DNA repair

The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons

CD22 Polyclonal Antibody, 100ul[BT-AP07329] Protein Analysis An important paralog of thisalternative products: Additional isoforms seem to exist,Contains 4 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2 containing phosphatases.,Mediates B cell B cell interactions. May be involved in the localization of B cells in lymphoid tissues. Binds sialylated

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