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UBC12 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction Four members of this family

SKU: 31139747745

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SEK141.00 SEK175.00

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UBC12 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction Four members of this familyThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes or E1s ubiquitin conjugating enzymes or E2s and ubiquitin protein ligases or E3s. This gene encodes a member of the E2 ubiquitin conjugating enzyme family. The encoded protein is linked with a ubiquitin like protein NEDD8

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Description

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC

This gene encodes a member of the WWC family of proteins| which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product

TFRC encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis

and tissue regeneration

This enzyme is closely related to a stimulator of iron transport (SFT)

UBC12 Rabbit Polyclonal Antibody, 100ul Nucleic Acid Extraction Four members of this familyThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes or E1s ubiquitin conjugating enzymes or E2s and ubiquitin protein ligases or E3s. This gene encodes a member of the E2 ubiquitin conjugating enzyme family. The encoded protein is linked with a ubiquitin like protein NEDD8

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