HBB Polyclonal Antibody, 100ul Serological Pipets Two isoforms of ZC3H13 exists

Two isoforms of ZC3H13 exists as a result of alternative splicing events

RIMs are active zone proteins that regulate neurotransmitter release

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family

The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'

A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream

HBB Polyclonal Antibody, 100ul Serological Pipets Two isoforms of ZC3H13 existsThe alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta zero thalassemia. Reduced amounts of detectable beta globin causes beta plus thalassemia. The order of the genes in the beta globin cluster is 5' epsilon gamma G