SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging CD1E encodes a member of

CD1E encodes a member of the CD1 family of transmembrane glycoproteins

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

There are about 3000 genes on chromosome 1 and considering the great number of genes there are also a large number of diseases associated with chromosome 1

which are thought to facilitate communication between the inside and outside environments of a cell

This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori

SHIP2(Phospho-Tyr986/987) Rabbit Polyclonal Antibody, 100ul Cell Screening and Imaging CD1E encodes a member ofThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.