AP2S1 Rabbit Polyclonal Antibody, 20ul Pipette Micro Tips Knockout studies in mice suggest

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

Post-translational modifications decrease the ability to chaperone

MIM:151410)

It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation

contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 Lys-9 trimethylation

AP2S1 Rabbit Polyclonal Antibody, 20ul Pipette Micro Tips Knockout studies in mice suggestOne of two major clathrin associated adaptor complexes, AP 2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants.