Mre11(Phospho-Ser676) Rabbit Polyclonal Antibody, 100ul Vessels This protein is a component

This protein is a component of several histone deacetylase complexes

The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis

which is characterized by severe growth defects

Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria

leukocytes

Mre11(Phospho-Ser676) Rabbit Polyclonal Antibody, 100ul Vessels This protein is a componentThis gene encodes a nuclear protein involved in homologous recombination telomere length maintenance and DNA double strand break repair. By itself the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA