BMAL1 (Acetyl Lys538) Polyclonal Antibody, 20ul Centrifugal Filter The gene resides on chromosome

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

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Alternatively spliced transcript variants encoding distinct isoforms have been identified for AK5

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BMAL1 (Acetyl Lys538) Polyclonal Antibody, 20ul Centrifugal Filter The gene resides on chromosomeThe protein encoded by ARNTL is a basic helix loop helix protein that forms a heterodimer with CLOCK. This heterodimer binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK ARNTL complexes. Defects in ARNTL have been linked to infertility,