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DSCR 1 Polyclonal Antibody, 50ul Molecular Biology and structural properties

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DSCR 1 Polyclonal Antibody, 50ul Molecular Biology and structural propertiesRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

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Description

and structural properties

each with a specific pattern of ligand binding and tissue distribution

Diseases associated with GPR158 include smallpox

also referred to as neurokinin A

|PTM:The trimeric structure of the NC1 domains may be stabilized by covalent bonds between Lys and Met residues

DSCR 1 Polyclonal Antibody, 50ul Molecular Biology and structural propertiesRegulator of calcineurin 1 encoded by RCAN1 interacts with calcineurin A and inhibits calcineurin dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of RCAN1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

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