NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Defects in this gene are

Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49)

tissue specificity:Expressed in normal mammary

Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules

This gene| a beta basic group member| is part of a gene cluster with beta-A4| beta-B1| and beta-B2

Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family

NSUN2 Rabbit Polyclonal Antibody, 50ul Cell Culture Plates Defects in this gene areThis gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5 methylcytosine (m5C) at position 34 of intron containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.