Dexras2 Polyclonal Antibody, 100ul Custom RNA Oligos Three transcript variants encoding different
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Dexras2 Polyclonal Antibody, 100ul Custom RNA Oligos Three transcript variants encoding differentRASD2 belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The RASD family member 2 functions as an E3 ligase for attachment of small ubiquitin like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1),
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