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TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets The encoded protein also functions

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TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets The encoded protein also functionsAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen

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Description

The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

This gene encodes a serine protease expressed exclusively in the thymus

FABPs may play roles in fatty acid uptake

The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex

TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets The encoded protein also functionsAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen

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