RGF1A Polyclonal Antibody, 100ul Antibody Development disease:Defects in F8 are the

disease:Defects in F8 are the cause of hemophilia A (HEMA)

The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

ADAM10 encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin

Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease

restores expression

RGF1A Polyclonal Antibody, 100ul Antibody Development disease:Defects in F8 are theGuanine nucleotide exchange factor (GEF) for KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.,Contains 1 N terminal Ras GEF domain.,Contains 1 Ras GEF domain.,tissue specificity: Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies.,