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IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 20ul[BT-AP08809] Culture Plate Inserts An important paralog of this

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IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 20ul[BT-AP08809] Culture Plate Inserts An important paralog of thisThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

An important paralog of this gene is CDK14

Mammals have three related thioredoxin reductases

that appear to have been derived from the piggyBac transposons

and both variants utilize alternative polyadenylation sites

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements

IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 20ul[BT-AP08809] Culture Plate Inserts An important paralog of thisThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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