M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller this gene is rearranged with

this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias

It is predominantly expressed in the pituitary gland

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

based on the arrangement of the first 2 of the 4 conserved cysteine residues

the binding site for calmodulin

M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller this gene is rearranged withThe protein encoded by this gene is the receptor for colony stimulating factor 1 a cytokine which controls the production differentiation and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF