BM28 Monoclonal Antibody, 100ul[BT-MCA0220] Pasteur Pipets and was shown to negatively

and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells

Studies suggest this is a cancer suppressor gene

It prevents assembly and promotes disassembly of microtubules

It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization

There is a pseudogene for this gene nearby on chromosome X

BM28 Monoclonal Antibody, 100ul[BT-MCA0220] Pasteur Pipets and was shown to negativelyThe protein encoded by this gene is one of the highly conserved mini chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6,