PTH/PTHrP-R Monoclonal Antibody, 100ul Peptide Modification MC5R encodes a member of

MC5R encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction

can bypass the interleukin 6 receptor (IL6R) and directly activate this protein

Its expression is regulated by IL2 activation of the cells

Mutations in this gene cause Charcot-Marie-Tooth disease| type 2A1

The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC)

PTH/PTHrP-R Monoclonal Antibody, 100ul Peptide Modification MC5R encodes a member ofThe protein encoded by this gene is a member of the G protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC),