p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging The protein encoded by this

The protein encoded by this gene is 75% identical to the mouse homolog

with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs

This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily

and is considered to be an oncogene

thereby releasing the attached protein from the plasma membrane

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging The protein encoded by thisTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.