ERK 1/2 Polyclonal Antibody, 50ul[BT-AP03057] Molecular Weight Markers A missense mutation in RBSN

A missense mutation in RBSN is associated with a defect in the early endocytic pathway

Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers

The complexity of SH3PXD2A isoforms is also evident in different cell types

The protein localizes to the nucleus and the cytoplasm

It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates

ERK 1/2 Polyclonal Antibody, 50ul[BT-AP03057] Molecular Weight Markers A missense mutation in RBSNMAPK1 (mitogen activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon