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TOPRS Polyclonal Antibody, 50ul Bottle-Top Dispenser The protein forms a homodimer

SKU: 34949129297

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SEK185.00 SEK235.00

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TOPRS Polyclonal Antibody, 50ul Bottle-Top Dispenser The protein forms a homodimerThis gene encodes a nuclear protein which is serine and arginine rich, and contains a RING type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.

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Description

The protein forms a homodimer embedded in the inner mitochondria membrane

which are G protein-coupled receptors

This gene encodes a protein containing a C3HC4-type RING finger domain| which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions

The protein encoded by LAT (linker for activation of T-cells) is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway

Mutations in SLC4A11 have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2

TOPRS Polyclonal Antibody, 50ul Bottle-Top Dispenser The protein forms a homodimerThis gene encodes a nuclear protein which is serine and arginine rich, and contains a RING type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.

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