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NCoA-3 Polyclonal Antibody, 50ul[BT-AP11732] Peptide Modification RAP1B and RAP2A small GTPases

SKU: 35314576342

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NCoA-3 Polyclonal Antibody, 50ul[BT-AP11732] Peptide Modification RAP1B and RAP2A small GTPasesThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several

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Description

RAP1B and RAP2A small GTPases that is activated by binding cAMP

This mitochondrial protein initiates the degradation of 1

cyclin L1 can be overexpressed and is therefore often considered a proto-oncogene

which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells

This complex plays a central role in inducing gene transcription during the immune response

NCoA-3 Polyclonal Antibody, 50ul[BT-AP11732] Peptide Modification RAP1B and RAP2A small GTPasesThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several

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