LYPLA1 Polyclonal Antibody, 20ul Centrifuges CBFA2T3 (CBFA2/RUNX1 translocation partner 3)

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression

leaving the NLS protein behind

It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells

An important paralog of this gene is FOXP3

hepatic cirrhosis

LYPLA1 Polyclonal Antibody, 20ul Centrifuges CBFA2T3 (CBFA2/RUNX1 translocation partner 3)LYPLA1 encodes a member of the alpha beta hydrolase superfamily. Acyl protein thioesterase 1 functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of LYPLA1 have been defined on chromosomes 4, 6, and 7.