DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments ABCC12 is a member of

ABCC12 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein (ATP binding cassette subfamily C member 12) contains two ATP-binding domains and 12 transmembrane regions

Mutations in this gene are associated with megalencep

|The C1 domain| containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B)| is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain

invasion and metastasis of cancer cells

2ml Rotor Adapter

DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments ABCC12 is a member ofCatalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). cofactor: Binds 2 magnesium ions per subunit. Residues 239 252 form a flexible loop which appears to affect the polymerase fidelity. Repair polymerase. Conducts "gap filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5' deoxyribose 5 phosphate lyase (dRP lyase) activity. PTM: Methylation by