Dkk-1 Polyclonal Antibody, 100ul Pasteur Pipets This protein forms transcriptional repressor

This protein forms transcriptional repressor complexes by associating with many different proteins

Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway

the interaction is direct and Ca(2+)-independent

or activity

Dkk-1 Polyclonal Antibody, 100ul Pasteur Pipets This protein forms transcriptional repressorDKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.