IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets Guanylate-binding protein 3 interacts with

Guanylate-binding protein 3 interacts with a member of the germinal center kinase family

This gene maps to a region of 19q13

May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles

Over-expressed in breast cancer

blood clotting

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 20ul Serological Pipets Guanylate-binding protein 3 interacts withThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.