SIK2 Polyclonal Antibody, 50ul Protein Research and has higher inhibitory activity

and has higher inhibitory activity when phosphorylated

Multiple pseudogenes have been identified for this gene

Angiogenesis has been shown to be essential for growth and metastasis of solid tumors

This gene encodes the human homolog of the proto-oncogene c-kit

and localizes to the Golgi apparatus

SIK2 Polyclonal Antibody, 50ul Protein Research and has higher inhibitory activityCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 175 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,Phosphorylates 'Ser 794' of IRS1 in insulin stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB specific