RAGP1 Polyclonal Antibody, 50ul Capsule Filter C6ORF55 encodes a protein involved

C6ORF55 encodes a protein involved in trafficking of the multivesicular body| an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al

The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature

however| imprinting of the human gene may be polymorphic| as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611)

as indicated for members 1-3

and with Senior-Loken syndrome type 4

RAGP1 Polyclonal Antibody, 50ul Capsule Filter C6ORF55 encodes a protein involvedThis gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP) binding and exchange. Alternative splicing results in multiple transcript variants.