FADD(Phospho Ser194) Polyclonal Antibody, 50ul Funnels Mutations in KRT17 lead to

Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family

An important paralog of this gene is SFT2D1

It interacts with MDM2 and enhances p53/TP53 ubiquitination

MME encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL)

FADD(Phospho Ser194) Polyclonal Antibody, 50ul Funnels Mutations in KRT17 lead toThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C terminal death domain, this protein can be recruited by TNFRSF6 Fas receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10 TRAIL receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N terminal