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SEPT9 Polyclonal Antibody, 100ul Oligo Pool Nuclear export mediator factor facilitates

SKU: 36994332969

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SEPT9 Polyclonal Antibody, 100ul Oligo Pool Nuclear export mediator factor facilitatesThis gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript

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Description

Nuclear export mediator factor facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin

remodelling of membrane lipids

and abnormal chromosome segregation

The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus

Besides the central nervous system| it is expressed at high levels in peripheral blood leukocytes| and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions

SEPT9 Polyclonal Antibody, 100ul Oligo Pool Nuclear export mediator factor facilitatesThis gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript

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