NR1H2 Polyclonal Antibody, 50ul Cryopreservation Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for HRH4

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Its ligand

This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins| which function in the mammalian early secretory pathway

Through obligatory heteromerization

NR1H2 Polyclonal Antibody, 50ul Cryopreservation Multiple transcript variants encoding differentThe liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand activated LXRs form obligate heterodimers