GHR Polyclonal Antibody, 100ul Cell Culture Dishes The predicted protein is proline-rich

The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains

It is expressed only in brain and ovary

The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation

Alternative splicing of this gene results in several transcript variants

This gene encodes a member of the toll-like receptor (TLR) family

GHR Polyclonal Antibody, 100ul Cell Culture Dishes The predicted protein is proline-richGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.