Stat6 Polyclonal Antibody, 100ul[BT-AP08644] Apoptosis & Autophagy This gene is part of

This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression

Mutations in this gene are associated with sensory/motor neuropathy with ataxia

Impaired spindle checkpoint function has been found in many forms of cancer

This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12

deleted in squamous cell lung carcinomas

Stat6 Polyclonal Antibody, 100ul[BT-AP08644] Apoptosis & Autophagy This gene is part ofThe protein encoded by STAT6 (signal transducer and activator of transcription 6) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses.