IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Plays a role in transcriptional

Plays a role in transcriptional activation of Wnt-responsive genes

Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus

Several pseudogenes have been identified

The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Plays a role in transcriptionalThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell