HAO1 Monoclonal Antibody(Mix), 50ul Immunoassays The adult expression of this

The adult expression of this gene is restricted to testes and ovaries

fetal and neonatal tissues

This gene is a member of the Sec-1 domain family| and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein

The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop

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HAO1 Monoclonal Antibody(Mix), 50ul Immunoassays The adult expression of thisThis gene is one of three related genes that have 2 hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two carbon substrate. The protein is also active on 2 hydroxy fatty acids. The transcript