Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter Two transcript variants that encode

Two transcript variants that encode different isoforms have been found for this gene

and binds to other proteins containing glutamine-rich regions

The encoded protein is involved in membrane trafficking and cell survival

Serine/threonine-protein kinase mTOR acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex

and inhibition of proliferation of tumor cells

Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter Two transcript variants that encodeCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.