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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath It shares limited sequence similarity

SKU: 38282045474

4.2
USD162.00 USD187.00

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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath It shares limited sequence similarityThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

It shares limited sequence similarity with iron-only bacterial hydrogenases

tongue and small intestine and in endocrine glands such as thyroid and adrenal gland

including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini

The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro

MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath It shares limited sequence similarityThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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