Stat5(Phospho Tyr694/699) Polyclonal Antibody, 100ul Custom DNA Oligos Breast cancer metastasis-suppressor 1 encoded

Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC)

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

tissue specificity:Highly expressed in brain

and stable gene expression

Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism

Stat5(Phospho Tyr694/699) Polyclonal Antibody, 100ul Custom DNA Oligos Breast cancer metastasis-suppressor 1 encodedThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM CSF, erythropoietin,