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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer The encoded protein has a

SKU: 38622778696

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CLCN5 Polyclonal Antibody, 20ul Vortex Mixer The encoded protein has aThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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Description

The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates

RAF1 and IRS1 proteins

It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins

These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons

and Biacore surface resonance analysis

CLCN5 Polyclonal Antibody, 20ul Vortex Mixer The encoded protein has aThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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